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Ivermectin is an anti-parasite medication. The trials so far have shown ivermectin reduces the number of cell-associated viral DNA by Click for further information on using ivermectin to treat COVID and other prevention and investigational treatments.
You will need to have a stool exam after taking ivermectin to make sure the infection is gone. Some patients may need to take another dose of ivermectin to treat the infection.
Ivermectin may make you feel dizzy. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Be careful going up and down stairs. It is not known whether ivermectin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
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Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ivermectin topical lotion in children.
However, use is not recommended in infants younger than 6 months of age. Appropriate studies have not been performed on the relationship of age to the effects of ivermectin topical cream in the pediatric population.
Safety and efficacy have not been established. Pregnancy Category C: Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
Breastfeeding: There are no adequate studies in women for determining infant risk when using this medication during breastfeeding.
Ivermectin is excreted into human milk in low concentrations. The manufacturer recommends that treatment during nursing only occur if the risk of delayed treatment to the mother outweighs the possible risk to the infant.
Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Allergic and inflammatory reactions the Mazzotti reaction may occur with ivermectin, probably due to the death of the microfilariae.
Patients treated with ivermectin therapy for onchocerciasis may experience these reactions in addition to clinical adverse reactions possibly, probably, or definitely related to the therapy itself.
The treatment of severe Mazzotti reactions has not been subjected to controlled clinical studies. After treatment with microfilaricidal medications, patients with hyperreactive onchodermatitis sowda may be more likely than others to experience severe adverse reactions, especially edema and aggravation of onchodermatitis.
Serious or fatal encephalopathy has been reported rarely in patients with onchocerciasis, and heavily infected with Loa loa, either spontaneously or after treatment with ivermectin.
This syndrome has been seen very rarely following the use of ivermectin therapy. Pretreatment assessment for loiasis and careful posttreatment follow-up should be implemented in all patients considered for treatment with ivermectin for any reason and who had exposure to Loa loa endemic areas of West and Central Africa.
The patient should be advised of the need for repeated stool examinations to document clearance of infection with Strongyloides stercoralis. The patient should be advised that treatment with ivermectin does not kill the adult Onchocerca parasites, and therefore repeated follow-up and retreatment is usually necessary.
In immunocompromised including HIV-infected patients being treated for intestinal strongyloidiasis, repeated courses of therapy may be necessary.
Adequate and well-controlled clinical trials have not been conducted in such patients to determine the optimal dosing regimen. Several treatments, i.
Control of extraintestinal strongyloidiasis in these patients is difficult, and suppressive therapy, i.
Ivermectin is extensively metabolized in the liver and should be used cautiously in patients with hepatic disease. Dosage adjustments may be needed, although specific recommendations are not currently available.
The manufacturer does not recommend that ivermectin treatment be excluded in patients with liver disease. Clinical trials of ivermectin did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients.
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